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Conversations with the people building AI

Building Durable AI Agents

Building Durable AI Agents

What does it take to move AI agents from demos to reliable production systems? In this episode, Hamza Tahir explores how MLOps principles are shaping the future of generative AI, covering workflows, agent harnesses, fleets, and the infrastructure needed to build durable, scalable systems. The conversation dives into…

47 MinutesPractical AI

How AI Learns to Smell with Alex Wiltschko - #771

How AI Learns to Smell with Alex Wiltschko - #771

In this episode, Alex Wiltschko, founder and CEO of Osmo, joins the show to discuss his goal of giving computers a sense of smell and what it takes to build olfactory intelligence. We explore the science behind smell, from the hundreds of olfactory receptors in the human nose to the challenge of mapping the…

1h 00mThe TWIML AI Podcast

Image Generation and Visual Intelligence with Black Forest Labs

Image Generation and Visual Intelligence with Black Forest Labs

How has AI image generation evolved from blurry outputs to powerful visual intelligence models? Dustin Podell, Co-Founder and Researcher at Black Forest Labs, explains the progression from diffusion to flow matching, how modern image models work, and how they're being used for image editing and practical visual…

48 MinutesPractical AI

AIUC-1: Building trust in AI agents

AIUC-1: Building trust in AI agents

How do we build trust in AI agents before the AI hailstorm arrives? Emil Lassen from the Artificial Intelligence Underwriting Company (AIUC) joins the show to discuss how the enterprise flywheel of standards, certification, audit, and insurance is being applied to AI agents. They explore the AIUC-1 framework, the…

45 MinutesPractical AI

Why AI Agents Break the GenAI Security Model with Devvret Rishi - #770

Why AI Agents Break the GenAI Security Model with Devvret Rishi - #770

In this episode, Sam talks with Dev Rishi, GM of AI at Rubrik, about what happens when agents move beyond answering questions and start taking action across tools, systems, and business processes. We explore why the enterprise playbook of static guardrails plus human approval starts to break down in the agent era.…

56 MinutesThe TWIML AI Podcast

Zero Trust for AI Agents

Zero Trust for AI Agents

As AI agents become more capable and autonomous, they also introduce new security challenges. In this 'Fully Connected' episode, Dan and Chris unpack Anthropic’s Zero Trust for AI Agents security framework and what it means for organizations deploying agentic systems. They examine the key security risks facing agentic…

47 MinutesPractical AI

Is RAG Dead? Lessons from Building AI for Tax Law with Alex Bowcut - #769

Is RAG Dead? Lessons from Building AI for Tax Law with Alex Bowcut - #769

As context windows grow into the millions of tokens, many AI practitioners are questioning whether retrieval-augmented generation (RAG) is still necessary. If modern models can ingest entire libraries of documents, why bother with retrieval at all? In this episode, Alex Bowcut, Head of Engineering at Sphere, explains…

52 MinutesThe TWIML AI Podcast

Breaking down the 2026 Stanford AI Index Report

Breaking down the 2026 Stanford AI Index Report

AI models can win math olympiads… but still struggle to read an analog clock. In this fully connected episode, Dan and Chris break down the latest Stanford AI Index Report and explore what it reveals about the current state of AI. They discuss AI adoption and safety, disappearing junior tech jobs, robotics, AI’s…

47 MinutesPractical AI

Rebooting Enterprise AI with MCP and Kubernetes

Rebooting Enterprise AI with MCP and Kubernetes

What happens when AI agents start acting less like chatbots and more like coworkers? In this episode, Dan and Chris sit down with Craig McLuckie, CEO of Stacklok to explore MCP, Kubernetes, ToolHive, enterprise AI, and the emerging infrastructure powering AI-native applications. From identity management to agent…

48 MinutesPractical AI

Relational Foundation Models for Enterprise Data with Jure Leskovec - #768

Relational Foundation Models for Enterprise Data with Jure Leskovec - #768

In this episode, Jure Leskovec, co-founder and chief scientist at Kumo and professor of computer science at Stanford, joins us to explore two fronts of his work: AI for science and relational deep learning. We begin with AI Virtual Cell, a multiscale effort to learn data-driven representations from proteins to cells…

1h 06mThe TWIML AI Podcast

Hermes Agent: Agents that grow with you

Hermes Agent: Agents that grow with you

Open Source AI is entering a new era, one shaped by self-improving AI Agents, recursive learning systems, and rapidly evolving AI Tools that blur the line between software and autonomous collaborators. In this episode, Daniel and Chris sit down with Nous Research co-founder and CTO Jeffrey Quesnelle to explore Hermes…

52 MinutesPractical AI

U.S. Congressman Beyer on AI challenges facing America and the World

U.S. Congressman Beyer on AI challenges facing America and the World

U.S. Congressman Don Beyer returns to Practical AI for another far-reaching conversation with Chris about many of the most important AI challenges facing America and the world. Blending political savvy and statesmanship with his unique technical understanding as an active Ph.D student in AI at George Mason University…

45 MinutesPractical AI